Entry List : Texas Motor Speedway
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- Texas Motor Speedway
- Alsco Uniforms 250
- Pole Winner: AJ Allmendinger
- Age: 39
- Team: No. 16 - Hyperice Chevrolet
- Owner: Kaulig Racing
- Crew Chief: Jason Trinchere
- Start positions set by NASCAR's Performance Metrics Qualifying (PMQ).
- AJ Allmendinger won the Pole Award for the Alsco Uniforms 250 by having the highest total PMQ.
- PMQ is a total number calculated on four performance metrics from the previous race:
- 15% of the driver's fastest lap time position.
- 25% of the driver's final race finish position.
- 25% of the owner's final race position.
- 35% of the Owner Points position.
- Drivers Entered: 42 (4 drivers will not make the race)
- Laps Scheduled: 167
- Laps Actual: 171 - NASCAR OVERTIME!
- Margin of Victory: 0.433 Seconds
- Time of Race: 2 Hours 22 Minutes 48 Seconds
- Average Speed: 107.773
- Cautions: 10 for 52 laps
- Lead Changes: 14
- Green Flag Passes: 1,104 (9.3 passes per green flag lap)
- Texas Motor Speedway
- 25th Annual Alsco Uniforms 250
- Race Winner: Kyle Busch
- Age: 36
- Team : No. 54 - Twix Toyota
- Owner: Coy Gibbs
- Crew Chief: Chris Gayle
- Kyle Busch won the 25th Annual Alsco Uniforms 250, his 99th victory in 360 Xfinity Series races.
- This is his second victory and second top-10 finish in 2021.
- This is his 10th victory and 18th top-10 finish in 24 races at Texas Motor Speedway.
- Justin Allgaier (second) posted his 11th top-10 finish in 23 races at Texas Motor Speedway. It is his seventh top-10 finish in 2021.
- Austin Cindric (third) posted his sixth top-10 finish in eight races at Texas Motor Speedway.
- Jade Buford (16th) was the highest finishing rookie.
- Austin Cindric leads the point standings by 108 points over AJ Allmendinger.
