Entry List : Darlington Raceway
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- Darlington Raceway
- In It To Win It 200
- Pole Winner: Sheldon Creed
- Age: 24
- Team: No. 2 - Liftkits4less.com Chevrolet
- Owner: GMS Racing
- Crew Chief: Jeff Stankiewicz
- Start positions set by NASCAR's Performance Metrics Qualifying (PMQ).
- Sheldon Creed won the Pole Award for the In It To Win It 200 by having the highest total PMQ.
- PMQ is a total number calculated on four performance metrics from the previous race:
- 15% of the driver's fastest lap time position.
- 25% of the driver's final race finish position.
- 25% of the owner's final race position.
- 35% of the Owner Points position.
- Drivers Entered: 38 (2 drivers will not make the race)
- Laps Scheduled: 147
- Margin of Victory: 0.531 Seconds
- Time of Race: 1 Hours 54 Minutes 23 Seconds
- Average Speed: 105.331
- Cautions: 8 for 35 laps
- Lead Changes: 4
- Green Flag Passes: 1,014 (9.1 passes per green flag lap)
- Darlington Raceway
- 2nd Annual In It To Win It 200
- Race Winner: Sheldon Creed
- Age: 23
- Team : No. 2 - Liftkits4less.com Chevrolet
- Owner: Maurice Gallagher, Jr.
- Crew Chief: Jeff Stankiewicz
- Sheldon Creed won the 2nd Annual In It To Win It 200, his eighth victory in 70 Camping World Truck Series races.
- This is his third victory and ninth top-10 finish in 2021.
- This is his second victory and second top-10 finish in three races at Darlington Raceway.
- John Hunter Nemechek (second) posted his second top-10 finish in two races at Darlington Raceway. It is his 13th top-10 finish in 2021.
- Stewart Friesen (third) posted his second top-10 finish in three races at Darlington Raceway.
- Chandler Smith (seventh) was the highest finishing rookie.
- Sheldon Creed has won four of the last five NASCAR Camping World Truck Series Playoff Races
